Session S8 - Nucleic Acids II.
ORAL session, Wednesday afternoon, March 24
510A, Palais des Congres
Melting and hybridization of DNA-coated gold nanoparticle networks are investigated with optical absorption spectroscopy and tansmission electron microscopy. Single-stranded DNA-coated nanogold are linked with complementary, single-stranded linker DNA to form particle networks. Network formation results in a solution color change, which can be used for DNA detection. Compared to free DNA, networked DNA-nanoparticle systems result in a sharp melting transition. Melting curves calculated from percolation theory agree with our experimental results(1).
(1) C.-H. Kiang, ``Phase Transition of DNA-Linked Gold Nanoparticles,'' Physica A, 321 (2003) 164--169.