
Session S8 - Nucleic Acids II.
ORAL session, Wednesday afternoon, March 24
510A, Palais des Congres
We have performed a series of experiments to study the aggregation and phase transtion of DNA-linked gold nanoparticle systems. Colloidal gold particles with diameter ranging from 10 to 40 nm are conjugated with thiol-modified single-stranded DNA. Based on the hybridization between complementary DNA single strands, three different types of DNA/nanoparticle networks can be obtained: (i) the ABL system; (ii) the AB system; and (iii) the AAL system. We study the particle size dependence of the aggregation and phase transition and compare the properties among different systems.