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Session S8 - Nucleic Acids II.
ORAL session, Wednesday afternoon, March 24
510A, Palais des Congres

[S8.009] Bioinformatics in the Thermodynamic Limit: Applications to pre-mRNA Splice Site Detection

Eric G. Daub, Daniel P. Aalberts (Williams College)

In the thermodynamic limit, physical systems exhibit predictable behavior. Traditional bioinformatics methods of matching patterns from a few cases can be superseded by alternate techniques when the number of instances approaches the thermodynamic limit. By enhancing an already large dataset, we find that we can differentiate real signals from decoys with superior accuracy. We apply our framework to the problem of precursor mRNA splice site detection in human sequences.

Part S of program listing